Ogata N, Ohishi Y (2002) Molecular diversity of structure and function of the voltage-gated Na+
channels. Jpn J Pharmacol 88(4):365–377
Oyibo SO, Prasad YDM, Jackson NJ, Jude EB, Boulton AJM (2002) The relationship between
blood glucose excursions and painful diabetic peripheral neuropathy: a pilot study. Diabet Med
19(10):870–873
Ozpolat B, Sood AK, Lopez-Berestein G (2014) Liposomal siRNA nanocarriers for cancer therapy.
Adv Drug Deliv Rev 66:110–116
Quattrini C, Tesfaye S (2003) Understanding the impact of painful diabetic neuropathy. Diabetes
Metab Res Rev 19:S2–S8
Roy ML, Narahashi T (1992) Differential properties of tetrodotoxin-sensitive and tetrodotoxin-
resistant sodium channels in rat dorsal root ganglion neurons. J Neurosci 12(6):2104–2111
Schreiber AK (2015) Diabetic neuropathic pain: physiopathology and treatment. World J Diabetes
6(3):432
Serrano-Sevilla I, Artiga Á, Mitchell SG, De Matteis L, de la Fuente JM (2019) Natural
polysaccharides for siRNA delivery: nanocarriers based on chitosan, hyaluronic acid, and
their derivatives. Molecules 24:2570
Setten RL, Rossi JJ, Ping HS (2019) The current state and future directions of RNAi-based
therapeutics. Nat Rev Drug Discov 18(6):421–446
Shende P, Patel C (2019) siRNA: an alternative treatment for diabetes and associated conditions. J
Drug Target 27:174–182
Shishkin V, Potapenko E, Kostyuk E, Girnyk O, Voitenko N, Kostyuk P (2002) Role of
mitochondria in intracellular calcium signaling in primary and secondary sensory neurones of
rats. Cell Calcium 32(3):121–130
Siau C, Xiao W, Bennett G (2006) Paclitaxel- and vincristine-evoked painful peripheral
neuropathies: loss of epidermal innervation and activation of Langerhans cells. Exp Neurol
201(2):507–514. https://linkinghub.elsevier.com/retrieve/pii/S0014488606002937
Simpson DM, Robinson-Papp J, Van J, Stoker M, Jacobs H, Snijder RJ et al (2017) Capsaicin 8%
patch in painful diabetic peripheral neuropathy: a randomized, double-blind, placebo-controlled
study. J Pain 18(1):42–53
Singleton JR, Smith AG, Bromberg MB (2001) Increased prevalence of impaired glucose tolerance
in patients with painful sensory neuropathy. Diabetes Care 24(8):1448–1453
Stino AM, Smith AG (2017) Peripheral neuropathy in prediabetes and the metabolic syndrome. J
Diabetes Investig 8(5):646–655
Subhan MA, Torchilin VP (2019) Efficient nanocarriers of siRNA therapeutics for cancer treatment.
Transl Res 214:62–91
Sultan A, Gaskell H, Derry S, Andrew RA (2008) Duloxetine for painful diabetic neuropathy and
fibromyalgia pain: systematic review of randomised trials. BMC Neurol 8:29
Ta LE, Bieber AJ, Carlton SM, Loprinzi CL, Low PA, Windebank AJ (2010) Transient receptor
potential vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice. Mol Pain 6:15
Tan T, Barry P, Reken S, Baker M (2010) Pharmacological management of neuropathic pain in
non-specialist settings: summary of NICE guidance. BMJ 340:c1079
Taylor CP, Angelotti T, Fauman E (2007) Pharmacology and mechanism of action of pregabalin:
the calcium channel α2-δ (alpha2-delta) subunit as a target for antiepileptic drug discovery.
Epilepsy Res 73(2):137–150
Tekade R, Maheshwari R, Sharma P, Tekade M, Chauhan A (2015) siRNA therapy, challenges and
underlying perspectives of dendrimer as delivery vector. Curr Pharm Des 21(31):4614–4636
Terashima T, Ogawa N, Nakae Y, Sato T, Katagi M, Okano J et al (2018) Gene therapy for
neuropathic pain through siRNA-IRF5 gene delivery with homing peptides to microglia. Mol
Ther Nucl Acids 11:203–215
Tesfaye S, Boulton AJM, Dickenson AH (2013) Mechanisms and management of diabetic painful
distal symmetrical polyneuropathy. Diabetes Care 36(9):2456–2465
384
R. Bhandari et al.